Business Wire

Brest University Hospital and HEMARINA Present Positive New Advances from the Initial Clinical Trial of HEMO2life® at the American Transplant Congress in Seattle

Jaa

Brest University Hospital and HEMARINA announced at a poster 1 session at the American Transplant Congress ( American Transplant Congress  "ATC") 2 , the leading global organ transplant congress, the interim 3-month results from the OxyOp 3 study, presented by Professor Yannick Le Meur, the trial's principal investigator. This study, conducted at six French transplant centres, followed, for one year, patients who had received a kidney that had been preserved in a solution containing the HEMO 2 life ® additive.

Brest University Hospital and HEMARINA had already published initial very positive results on the safety in use of HEMO2life® in November 2017 (click here for more details), namely:

  • No product-related graft loss, according to the Independent Data Safety Monitoring Board (IDSMB),
  • No death at 3 months,
  • No major adverse event related to HEMO2life®,
  • No immunological, allergic or pro-thrombotic effects,
  • Promising preliminary efficacy data.

The new results presented confirm this major medical innovation in kidney transplants. In terms of efficacy, two major results should be noted:

  • Fewer patients who received a kidney preserved with HEMO2life® suffered from Delayed Graft Function (DGF): 6.98% vs 26.19%. This marker, the DGF, is predictive of the long-term success of the transplant,
  • Another blood parameter, like serum creatinine, which indicates a defect in the elimination of organ waste in the blood, also marked the difference between the two patient groups; patients whose kidneys had been preserved with HEMO2life® reached target levels of serum creatinine in an average of 7 days, compared with an average of 13 days in the other patient group. Moreover, this parameter is usually studied to assess the success of a kidney transplant.

Professor Yannick Le Meur, Nephrologist, University Professor, Head of Department at Brest University Hospital, stated "HEMARINA's technology is extremely promising: its use by the surgical teams is simple and can easily be integrated into current practices. It should make the teams' work easier by giving them more time to prepare transplants. I am therefore very pleased to present the results of this world first to the entire scientific community gathered at the ATC and to be able to share them with colleagues worldwide".

Dr Franck Zal, co-founder and CEO of HEMARINA added: "We are delighted with the results obtained. HEMO 2 life ® enables delayed graft function to be reduced by almost two-thirds. This criterion is a predictor of the long-term survival of the transplant and unambiguously demonstrates excellent preservation of the graft compared with existing clinical techniques. We are fully committed to bringing this medical device onto the market. We expect HEMO 2 life ® to very rapidly become the benchmark in graft preservation. These clinical results contribute to strengthening our technological platform. A transplant is so precious that we should give it every chance of success. We owe it to the donors, the receivers, and their respective families".

1 Poster: reference D48 presented on Tuesday 5 June 18:00 – 19:00, Hall 4 EF
2 ATC: global congress for Health professionals who are interested in the clinical and research aspects of organ transplantation. It brings together 5,000 participants and exhibitors
3 OxyOp: evaluation of a marine OXYgen carrier, HEMO2life®, for hypOthermic kidney graft preservation before transplantation (first human clinical study of a marine oxygen carrier).

References:

Congress website: https://atcmeeting.org/
Programme: https://atcmeeting.org/sites/default/files/docs/2018/atc2018_cti_program_4-30-18.pdf

Further information on the OxyOp trial can be found at https://www.clinicaltrials.gov./

For more information, visit our website: www.hemarina.com

Contact information

Actifin
Jenna Driff, Tel: +33-(0)1-56-88-11-21
E-mail: jdriff@actifin.fr

Tietoja julkaisijasta

For more than 50 years, Business Wire has been the global leader in press release distribution and regulatory disclosure.

Tilaa tiedotteet sähköpostiisi

Haluatko tietää asioista jo ennen kuin ne uutisoidaan? Kun tilaat tiedotteemme, saat ne sähköpostiisi yhtä aikaa suomalaisen median kanssa. Tilauksen voit halutessasi perua milloin tahansa.

Lue lisää julkaisijalta Business Wire

Moody’s Completes Acquisition of Omega Performance21.8.2018 00:06Tiedote

Moody’s Corporation (NYSE:MCO) announced today that it has completed its acquisition of Omega Performance, a leading provider of online credit training. Moody’s announced its intention to acquire Omega Performance, a business unit of TwentyEighty Inc, on July 8, 2018. Omega Performance offers a wide range of online credit training courses to clients worldwide and serves more than 300 customers, ranging from large global banks to local lending institutions. The acquisition will enhance Moody’s Analytics as a worldwide market standard in credit proficiency for financial institutions that offer consumer, small business and corporate lending. The acquisition of Omega Performance is not expected to have a material impact on Moody’s 2018 financial results. For further information about Moody’s Analytics eLearning solutions, visit www.moodysanalytics.com/elearning-courses. ABOUT MOODY'S CORPORATION Moody's is an essential component of the global capital markets, providing credit ratings, rese

Pacific Drilling Announces Settlement in Mediation Between Quantum Pacific and Ad Hoc Group of Creditors20.8.2018 17:02Tiedote

Pacific Drilling S.A. (OTC:PACDQ) (“Pacific Drilling” or the “Company”) today announced that its plan of reorganization filed on July 31, 2018 (the “Plan”), based on a proposal presented to the Company’s Board of Directors by an ad hoc group of its secured creditors (collectively, the “Ad Hoc Group”), now has the full support of the Company’s majority shareholder, Quantum Pacific (Gibraltar) Limited (“QP”). The Plan was already supported by all of the Company’s major creditor interests. With QP’s participation, the Company expects a smooth plan confirmation process and a quick emergence from its Chapter 11 proceedings. Pacific Drilling CEO Paul Reese commented, “The agreement reached by QP and the Ad Hoc Group delivers the final piece needed to make the Company’s Plan a consensual one that has the support of the Company’s major stakeholders. The agreement should allow the Plan to move forward efficiently and expeditiously through the implementation and confirmation process.” Pursuant t

Bella Hadid Headlines True Religion’s Latest Campaign20.8.2018 15:32Tiedote

True Religion has tapped Bella Hadid to be the face of the brand. The supermodel embodies all things True Religion, past, present and future; iconic, edgy and everlasting. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20180820005283/en/ Bella Hadid Headlines True Religion’s Latest Campaign (Photo: Business Wire) An inherit fan of the brand, Bella was the natural choice to meld the iconic essence of the brand with the modern view of its future. An all-star team was assembled including photographer Boo George, stylist Mimi Cuttrell, and hair and makeup duo Jen Atkin and Mary Phillips to create imagery and complementary looks that usher True Religion into a new era that honors the heritage of the brand. A quintessential, confident LA girl with roots at home and abroad, Bella’s voice was not only an inspiration, but an integral part in imagining this campaign, envisioning the brand through her eyes for the next generation of True

FRISS Brings Claim Fraud Analysis to a Next Level With Web-IQ´s Innovative Online Network Solution20.8.2018 14:30Tiedote

Asking your neighbor or friend to sign as a witness to a claim for car damages at your insurance company will work no more, with the new Claim Fraud Analysis feature of FRISS. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20180820005039/en/ Eldert van Wijngaarden (Web-IQ) and Philip van Waning (FRISS) shaking hands. (Photo: Business Wire) FRISS, the worldwide provider of AI powered fraud and risk solutions for the P&C insurance industry, recently added a new and innovative feature in their fraud analytics solution: Online Network Analysis from Web-IQ. This feature automatically identifies if the claimants and the insured or other involved persons are related to each other in an on-line environment. This is a proven and strong indicator for fraudulent claims. Especially with car accidents and other types of claims where multiple persons are involved, it adds a whole new approach to the traditional claim analyses. “Research sho

Veristat Congratulates Alnylam on the FDA Approval of ONPATTRO™ (patisiran)20.8.2018 14:30Tiedote

Veristat, a full service Clinical Research Organization (CRO), congratulates Alnylam on the recent FDA approval of ONPATTRO™ (patisiran), a lipid complex injection for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. “On behalf of the entire Veristat team that has supported Alnylam in the development of this therapy, we are humbled to have contributed towards this first-in-class drug approval for Alnylam, for the patients with hATTR amyloidosis and their families,” said John P. Balser, Ph.D., President and Co-Founder of Veristat. “We are continuing to support Alnylam as they look to expand regulatory approval of this treatment to other regions of the world.” Veristat began working with Alnylam over 11 years ago and helped design the studies and prepare the Investigational New Drug (IND) submission for patisiran. Our collaboration continued throughout the entire patisiran program inclusive of a phase 2 study, a phase 3 pivotal study

Global IBC Future Zone and IABM Future Trends Theatre to Explore the Latest Tech Shaping the Industry20.8.2018 14:18Tiedote

IBC2018, the world’s most influential media, entertainment and technology show, today announces the line-up for the IBC Future Zone and IABM Future Trends Theatre. Well established as part of the IBC Exhibition, from 14-18 September, the Future Zone brings together the very latest ideas, innovations and concept technologies from international industry and academia and showcases them in a single specially-curated area sitting alongside exhibition Hall 8. This year, the focus is on showing how new technologies grow from their first inception and progress through to research, development, and validation projects; right through to maturing into the ground-breaking applications and future product standards. Major industry trail-blazers presenting their visions of the future, include Japan’s NHK and BBC R&D from the UK. Both companies will demonstrate a number of technology advances, including: Web-VR applications; object-based media scenarios; pathways to 8K resolution for UHD; and Artifici

Uutishuoneessa voit lukea tiedotteitamme ja muuta julkaisemaamme materiaalia. Löydät sieltä niin yhteyshenkilöidemme tiedot kuin vapaasti julkaistavissa olevia kuvia ja videoita. Uutishuoneessa voit nähdä myös sosiaalisen median sisältöjä. Kaikki STT Infossa julkaistu materiaali on vapaasti median käytettävissä.

Tutustu uutishuoneeseemme