PKU GOLIKE Debuts at SSIEM 2018 Conference: Science Driven Innovation behind the Medical Food for PKU Management of APR Applied Pharma Research
APR Applied Pharma Research s.a. (“APR”), the Swiss independent developer of science driven and patent protected healthcare products, has successfully concluded its participation at the recent SSIEM (Society for the Study of Inborn Errors of Metabolism) Conference held in Athens. The company has taken advantage of this international event, gathering around 3.000 physicians involved in inherited metabolic diseases, to showcase PKU GOLIKE®, the innovative Phenylalanine (Phe)-free medical food formula for Phenylketonuria (PKU), powered by the patented Physiomimic Technology TM .
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20180913005450/en/
PKU GOLIKE. Feel the change: Join the evolution in nutritional management (Photo: APR Applied Pharma Research)
PKU GOLIKE® is a brand new generation of medical food formulas for oral use consisting of a prolonged released amino acid (AA) mixture without Phe (with or without vitamins and minerals), providing a physiological absorption of the AAs as well as a remarkable masking of odor and taste, while minimizing the unpleasant after-taste typical of free AAs.
The large attendance at APR’s sponsored satellite symposium “Physiological Absorption of Amino Acids: Rationale and Expected Benefits”, involving renown international experts in PKU, represented the ideal occasion to divulge details regarding PKU GOLIKE® and the Physiomimic TechnologyTM . During the symposium, it was highlighted how this drug delivery technology can effectively prolong the release of the amino acids (AAs) and support their physiological absorption.
In particular, a study in human subjects demonstrated that significant reductions of the AAs absorption peaks were obtained with PKU GOLIKE®, when compared with the same AAs mixture without the application of the technology. The reduction of the absorption peaks, associated with a similar bioavailability of the AAs, allows reducing AA fluctuations in favor of an improved efficiency in the use of AAs.
The same cross over human study also demonstrated a reduction of Phe fluctuations over time, deriving from body metabolism of the study subjects receiving Phe-free PKU GOLIKE® in fasting conditions, with respect to the fluctuations measured when free AAs were consumed.
Overall, the scientific data of PKU GOLIKE® presented at this meeting open new avenues for research in nutrition, aimed at providing data useful to patients to improve the efficiency of the dietary management of their disorder.
Throughout the lifetime of the event, APR’s staff has been very busy at the company booth with welcoming a high number of physicians from all over the world eager to gather more information about PKU GOLIKE®. Visitors’ questions regarded, in particular, the patented Physiomimic™ Technology - how it works and the benefits of its application to the innovative amino acids mixture. They also had the chance to get to know PKU GOLIKE® range, made of three different AA mixes suitable for PKU patients of different ages, as well as to experience the special coating micro granules containing the exclusive formulation of AAs.
Physicians and dieticians who tasted the product were extremely surprised to find out how the Physiomimic Technology TM is actually able to remarkably mask the unpleasant taste and odor of AAs, thus being confirmed on the extent of this significant advantage for PKU patients’ compliance to dietary regimen.
The venue offered also the opportunity to arrange several meetings with potential business partners, who could appraise the extent of the company innovation appeal and be informed about APR’s projects in the inherited metabolic diseases.
“We are very pleased by the positive reactions of the medical community to our innovation. As father of a PKU child, I was quite conscious of the clinical and nutritional gaps in PKU management still unresolved. We decided to apply our deep know-how in drug delivery technologies and systems to offer to PKU patients’ a new treatment option, the benefits of which are confirmed by the preclinical and clinical data generated so far.” said Paolo Galfetti, CEO of APR Applied Pharma Research. “Now, we look forward to take to fruition of PKU patients and care givers this innovative product line and to further support our innovation by generating additional scientific data in the coming future”.
About Phenylketonuria or PKU
Phenylketonuria or PKU is a rare, genetic, recessive metabolic disorder affecting about 50.000 people worldwide. PKU is characterized by the deficiency or the malfunctioning of a liver enzyme needed to process phenylalanine (“Phe”), an essential amino acid found in most protein-containing food. Excessive amounts of Phe in the bloodstream become toxic to the brain, impairing the normal development of the central nervous system. If not properly treated, PKU leads to severe, non-recoverable mental retardation and major cognitive disabilities. PKU can only be treated through a strict, life-long, low-protein (low-Phe) dietetic treatment combined with a daily assumption of low-protein modified foods and medical food, which provides Phe-free amino acids and other important nutrients, needed due to the dietary restrictions of PKU patients.
About APR Applied Pharma Research s.a.
APR is a Swiss, independent developer of science driven, patent protected healthcare products. The Company identifies, develops and licenses, value added products designed to address patient or consumer needs in niche or rare therapeutic areas on a global basis. In particular, APR’s business model is currently focused on two pillars: (i) internally developed and financed (alone or together with co-development partners) proprietary, value added products to be licensed to healthcare companies for their commercialization, and (ii) support to third party projects by offering added value R&D services under contract and fee for service arrangements. APR has a balanced pipeline of revenue generating branded products marketed in all major markets, combined with a compelling pipeline of products at different stages of development. APR has entered into licensing and partnership agreements with pharmaceutical companies in over 70 countries, with international sales on a worldwide basis.
For more information about Physiomimic™ Technology, please visit: www.apr.ch/apr-pharmaproducts/medical-prescription/genetic-metabolic-disease/
APR Applied Pharma Research s.a.:
Paolo Galfetti, +41 91 6957020
Chief Executive Officer
For more than 50 years, Business Wire has been the global leader in press release distribution and regulatory disclosure.
Tilaa tiedotteet sähköpostiisi
Haluatko tietää asioista ensimmäisten joukossa? Kun tilaat mediatiedotteemme, saat ne sähköpostiisi välittömästi julkaisuhetkellä. Tilauksen voit halutessasi perua milloin tahansa.
Lue lisää julkaisijalta Business Wire
Kao Data Invests in euNetworks High Density Fibre as Part of a North London Artery11.12.2018 12:07 | Tiedote
Kao Data, the home of innovation and UK’s leading entrant to the wholesale colocation market, has announced it is working with euNetworks, a Western European bandwidth infrastructure provider. This enables the delivery of high-density fibre and duct to the Kao Data, Harlow based data centre campus north of London. The new infrastructure provides unique routing opportunities, taking advantage of Harlow’s strategic location between core hyperscale campuses in Dublin and Amsterdam. It also offers fast connection to Slough, to the West of London, and Docklands in the East of London. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181211005308/en/ Kao Data Invests in euNetworks High Density Fibre as Part of a North London Artery (Photo: Business Wire) As the UK continues its strong position in the international data centre market, a series of significant investments in high-density fibre routes are underway to support hyperscale d
Spirent Helps High-Speed Setup For Aston Martin Racing11.12.2018 11:00 | Tiedote
Spirent Communications plc (LSE:SPT), the world leader in test, measurement, assurance, and analytics solutions for next-generation devices and networks, today announced that Aston Martin Racing (AMR) is using its Test as a Service (TaaS) platform, iTest, to assist the iconic automotive brand’s bid for FIA World Endurance Championship GTE category success. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181211005239/en/ Spirent's technical partnership with Aston Martin Racing has dramatically reduced the team's high-speed LAN test and set-up time at FIAWEC events. (Photo: Business Wire) Aston Martin Racing deploys a high-speed local area network (LAN) trackside to connect team drivers and cars with the pit crew, engineers and managers on pit lane, to carry radio communications, telemetry and video data. The FIAWEC Super Season includes some of the world’s most grueling tests of driver and car – including the famous Le Mans 24
WaveOptics Raises $26m to Scale Business and Support International Expansion in Its First Stage of Series C Funding11.12.2018 11:00 | Tiedote
WaveOptics, the world leading designer and manufacturer of diffractive waveguides for use in Augmented Reality (AR) wearables, has raised $26 million (£20m) from existing shareholders and new investors. The capital raised will be used to scale up the business operations on a national and international basis. This round was led by Octopus Ventures, one of WaveOptics’ largest shareholders and one of Europe’s most prominent venture capital firms. The fundraise was supported by other existing shareholders including IP Group, Robert Bosch Venture Capital and Gobi Partners, as well as new investors Goertek and Optimas Capital Partners. David Hayes, WaveOptics CEO, commented: “We have made excellent progress over the last year with our high performing, manufacturable, and versatile waveguides. We are now working with a wide range of leading global OEMs and ODMs as they ramp up the development of their products. “These additional funds will enable us to scale up rapidly around the world, parti
Yamaha Motor Outline of Long-term Vision & New Medium-term Management Plan11.12.2018 09:05 | Tiedote
Yamaha Motor Co., Ltd. (TOKYO:7272) announced today that it has formulated its long-term vision until 2030, and a New Medium-term Management Plan for the three-year period starting in 2019. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181210005244/en/ (Photo: Business Wire) For its long-term vision, Yamaha Motor has created the slogan “ART for Human Possibilities” and devised a growth strategy heading for 2030. For increasingly diversifying people's values and the environment around societies, the Company will implement its growth strategies while promoting solutions to social issues based on its own historical values. While maintaining the earning power from existing businesses, the new medium-term management plan will allocate resources to strategic growth areas such as new business, and work toward achieving consolidated net sales of 2-trillion yen and a consolidated operating income of 180 billion yen. View source vers
Egon Zehnder Global Board Diversity Tracker Suggests Gender Parity in the Boardroom May Never Be Achieved11.12.2018 09:01 | Tiedote
Egon Zehnder, the world's leadership advisory firm, today released the results of its 2018 Global Board Diversity Tracker. The study shows the accelerating growth seen in female directors in Western Europe is now levelling off, and growth elsewhere remains sluggish, suggesting gender parity on boards may never be reached at the current pace. The research, examining data from 1610 public companies with market caps above €7bn in 44 different countries, shows that despite the slow improvement in the number of women on boards, nearly three quarters of all new board positions worldwide still go to men. Jill Ader, Chairwoman of Egon Zehnder, said: “We need diversity, but it’s simply not happening fast enough. New voices and perspectives are essential to unlock the transformational capabilities that businesses tell us they need. Companies - starting from the very top - have to recognize the impact that a critical mass of women on the board and the executive committee makes and take the steps
Rootstock Software Announces New International Channel Partners11.12.2018 09:00 | Tiedote
Rootstock Software, a leading cloud Enterprise Resource Planning (ERP) provider for manufacturing, distribution and supply chain organizations on the Salesforce Platform, announced today that the company is continuing to experience significant international growth with the signing of several new partners. These partners will provide Rootstock customers in Europe, the Middle East and Southeast Asia with consulting and implementation services for the company’s Cloud ERP solution. Rootstock Cloud ERP is a flexible, modern and digitally connected ERP solution that provides organizations with real-time management across their entire business, including manufacturing, distribution, supply chain and finance operations. Rootstock’s channel partners will help customers achieve their digital transformation and business goals by leveraging Rootstock to better connect customers, suppliers and employees. When combined with Salesforce, Rootstock Cloud ERP customers enjoy a 360-degree view of all cus
Uutishuoneessa voit lukea tiedotteitamme ja muuta julkaisemaamme materiaalia. Löydät sieltä niin yhteyshenkilöidemme tiedot kuin vapaasti julkaistavissa olevia kuvia ja videoita. Uutishuoneessa voit nähdä myös sosiaalisen median sisältöjä. Kaikki STT Infossa julkaistu materiaali on vapaasti median käytettävissä.Tutustu uutishuoneeseemme