Exscientia Receives Open Philanthropy Grant to Explore New Therapeutic Approach for Pandemic Influenza
Exscientia plc (Nasdaq: EXAI) announced today that the Company received a $2.3 million grant from Open Philanthropy, a philanthropic funder with several programs in global health and wellbeing. Under this grant, Exscientia aims to harness the activation of the host interferon response as a therapeutic approach for pandemic influenza.
The grant comes in the context of the wider Pandemic Antiviral Discovery (PAD) initiative. Out of the COVID-19 pandemic experience, jointly with the Novo Nordisk Foundation and the Bill & Melinda Gates Foundation, Open Philanthropy launched the PAD initiative to help catalyse the discovery and early development of novel antiviral medicines in preparation for future pandemics.
“We are thrilled that these expert institutions are supporting Exscientia’s capabilities to develop innovative solutions to address significant unsolved health issues, expressed through this grant,” said Professor Ian Goodfellow, Vice President of Antivirals at Exscientia. “If we manage to ‘turn on’ the interferon response, in a highly controlled manner using small molecule therapeutics, we may be able to transform the way influenza can be treated and prevented in the future – an essential requirement of effective pandemic preparedness.”
The research funded through this grant will allow Exscientia to further explore the requirements for the activation of key aspects of the interferon response of known antiviral effects against influenza and COVID-19. The interferon response is a crucial component of the body’s natural ability to control influenza virus infection. Its activation results in the production of soluble proteins that bind to the surface of epithelial cells that line the respiratory tract and activate an antiviral state, suppressing further viral replication.
This focus aligns with the company’s ongoing commitment to pandemic preparedness, initiated with support from the Bill & Melinda Gates Foundation in 2021. Over the long-term, by utilising Exscientia’s AI-led drug discovery platform, the research funded through this grant and any resulting chemical hits may bear potential to be used in the design of potent and specific small molecule drug candidates able to turn on the interferon response in select tissues or cells relevant to influenza virus infection, including future variants and other viruses.
“We are excited to help fund novel approaches to increasing resilient response to infectious disease,” said Heather Youngs, Senior Program Officer for Scientific Research at Open Philanthropy. “The world needs diverse ready options to address general global health needs and to prevent future pandemics and all their dire consequences.”
Exscientia is an AI-driven precision medicine company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting. Our internal pipeline is focused on leveraging our precision medicine platform in oncology, while our partnered pipeline broadens our approach to other therapeutic areas. By pioneering a new approach to medicine creation, we believe the best ideas of science can rapidly become the best medicines for patients.
Exscientia Forward-Looking Statements
This press release contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Any statement describing Exscientia’s goals, plans, expectations, financial or other projections, intentions or beliefs is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to a number of risks, uncertainties and assumptions. In light of these risks and uncertainties, and other risks and uncertainties that are described in the Risk Factors section and other sections of Exscientia’s Annual Report on Form 20-F, filed with the Securities and Exchange Commission (SEC) on March 23, 2022 (File No. 001-40850), and other filings that Exscientia makes with the SEC from time to time (which are available at https://www.sec.gov), the events and circumstances discussed in such forward-looking statements may not occur, and Exscientia’s actual results could differ materially and adversely from those anticipated or implied thereby. Although Exscientia’s forward-looking statements reflect the good faith judgement of its management, these statements are based only on facts and factors currently known by the Company at the time of this press release. As a result, you are cautioned not to rely on these forward-looking statements.
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
About Business Wire
For more than 50 years, Business Wire has been the global leader in press release distribution and regulatory disclosure.
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Mavenir in Collaboration with Intel Delivers Optimised Performance and Power Efficiency for 4G and 5G Open vRAN Solution24.2.2024 14:37:00 EET | Press release
Mavenir, the cloud-native network infrastructure provider building the future of networks, today announces availability of its cutting-edge Open vRAN solution powered by 4th Gen Intel Xeon Scalable processors with Intel vRAN Boost – delivering a cloud-native, high-performance and energy-efficient solution for latency-sensitive and compute-intensive mobile network applications. The move to Intel’s recent processors for vRAN marks the latest solution optimisation for Mavenir, which has driven Open RAN momentum through three generations of Intel Xeon Scalable processors. Mavenir's Open vRAN solution, powered by 4th Gen Intel Xeon Scalable processors with Intel vRAN Boost, offers an exceptional suite of performance, functionality, and integrated artificial intelligence (AI) and machine learning (ML) application for the next generation 4G and 5G networks. Mavenir has built a close and long-standing technology collaboration with Intel, and the adoption of Intel’s processors enables the devel
itel Grand 2024 Brand Launch, the Industry's Biggest Event at the Egyptian Pyramids23.2.2024 20:35:00 EET | Press release
itel, the global leading smart life brand committed to providing affordable and good quality consumer electronic products, is poised to redefine its visual identity with the spectacular launch of its new logo at the iconic Great Pyramids of Giza in Egypt on February 22. This momentous occasion will not only mark a significant evolution in itel’s brand image but also serve as a platform to engage and celebrate with esteemed partners and customers worldwide, especially customers from the Middle East and North Africa region. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20240222762808/en/ itel successfully launched its 2024 brand launch event at Egyptian Pyramids (Photo: Business Wire) The unveiling ceremony at the Egyptian Pyramids signifies itel’s commitment not only to technological innovation but also to creating a memorable and immersive experience for attendees. The event will kick off with a breathtaking display of openin
Toshiba at EuroCIS: Delivering Solutions to Empower Retailers to Go Beyond23.2.2024 19:43:00 EET | Press release
At EuroCIS 2024, Toshiba Global Commerce Solutions showcases how retailers can “Create Beyond what’s Possible” to transform retail operations and customer experiences with its innovative solutions portfolio (booth in hall 9 #B42). The international trade fair will take place on February 27-29 in Düsseldorf, Germany. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20240223284358/en/ At EuroCIS 2024, Toshiba Global Commerce Solutions will empower retailers to transform their operations and customer experiences with innovative solutions and services. (Photo: Business Wire) “Our unified commerce and self-service solutions help retailers create shopping experiences that go beyond consumer expectations,” says Meike Marquardt, Head of Marketing for Europe, Toshiba Global Commerce Solutions. “With Toshiba Global Commerce Solutions as a trusted partner, retailers have the power to adapt effortlessly to the rapidly changing business need
Adtran confirms compliance with final BABA ruling and continues US investment23.2.2024 19:40:00 EET | Press release
Adtran today announced its readiness to support the Broadband Equity Access and Deployment (BEAD) program, welcoming the clarity and guidance provided by the Build America, Buy America (BABA) rule. With its commitment to US-based manufacturing spanning three decades, Adtran is at the forefront of the market with BABA-compliant fiber access solutions ready to enhance nationwide connectivity, economic growth and the digital inclusivity of communities across America. With 42.5 billion USD allocated for grants, the BEAD program aims to connect millions of underserved homes in the USA to high-speed broadband and has a mandate for domestically produced equipment. Adtran will supply BABA-compliant optical line terminals (OLTs), cabinets, ONTs and pluggable optics, providing a comprehensive solution fully ready to meet the needs of the BEAD program. These offerings will soon be showcased on the NTIA’s certification website. This press release features multimedia. View the full release here: ht
Mavenir and Terrestar Solutions Partner to Accelerate Commercial Deployment of 5G New Radio Non-Terrestrial Network23.2.2024 18:49:00 EET | Press release
Mavenir, the cloud-native network infrastructure provider building the future of networks, continues its pioneering leadership in Open RAN with 5G New Radio (NR) Non-Terrestrial-Network (NTN) solutions. The latest initiative is to integrate satellite connectivity for Open RAN terrestrial networks thereby enabling seamless connectivity for users across satellite and terrestrial networks. The project is being delivered in collaboration with Terrestar Solutions, a Canadian based Satellite Operator. Satellite Operators are actively looking at ways to harness 5G NTN capabilities within their network topology, to extend coverage and capacity in areas where traditional terrestrial networks may be economically unfeasible or impractical. Terrestar will launch a new Narrowband IoT (NB-IoT) service offer to the market, evolving to a full 5G Direct to Device (D2D) service by 2025. As the chosen technology supplier, Mavenir will provide the enabling 3GPP standards-compliant Core and O-RAN interface
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.Visit our pressroom