Business Wire

Bioptimus Launches H-optimus-0, the World's Largest Open-Source AI Foundation Model for Pathology


Less than five months after its launch, French startup Bioptimus has announced the release of H-optimus-0, the world’s largest open-source AI foundation model for pathology. With 1.1 billion parameters, H-optimus-0 is trained on a proprietary dataset of several hundreds of millions of images extracted from over 500,000 histopathology slides across 4,000 clinical practices. This sets a new benchmark for state-of-the-art performance in several critical medical diagnostic tasks, from identifying cancerous cells to detecting genetic abnormalities in the tumor.

This press release features multimedia. View the full release here:

Rodolphe Jenatton, CTO of Bioptimus: “Having launched less than five months ago, we are excited to introduce H-optimus-0, a fully open-source model that represents a significant leap forward in the field of pathology. We are committed to advancing medical research and improving patient care. By encouraging collaboration and the adoption of new practices, we aim to speed up innovations in pathology and beyond, ultimately benefiting patients worldwide.”

Pathology is the cornerstone of disease diagnosis, requiring meticulous examination of tissue samples to identify abnormalities. Traditionally, this process relies heavily on pathologists' expertise and experience. However, the increasing complexity and volume of cases necessitate advanced tools that can assist pathologists in making faster, more accurate diagnoses.

H-optimus-0 Key Features and Capabilities

  • Unmatched Scale and Performance: With 1.1 billion parameters, H-optimus-0 is the largest open-source AI model tailored specifically for pathology, ensuring comprehensive analysis and high accuracy.
  • Extensive Training Dataset: Trained on a vast dataset of over 500,000 pathology slides, H-optimus-0 has been exposed to a diverse array of cases, enabling it to generalize effectively across different diagnostic scenarios.
  • State-of-the-Art Diagnostics: H-optimus-0 achieves state-of-the-art performance in several key diagnostics tasks, consistently meeting the performance or outperforming existing models and setting new standards in the field. The model was assessed on 5 tile-level tasks to identify tissue types or tissue characteristics and 6 slide-level tasks to detect the presence of biomarkers or the presence of metastasis across several cancer types.
  • Open Source Availability: As an open-source model, H-optimus-0 can be utilized by researchers to accelerate the development of novel digital pathology models and will foster collaboration among researchers, clinicians, and developers, driving further advancements and solutions in pathology AI.

With its unprecedented scale and depth of training within the open-source community, H-optimus-0 leverages cutting-edge AI technology to enhance the precision and efficiency of pathology diagnostics.

Professor Jean-Philippe Vert, PhD, co-founder and CEO of Bioptimus, said: “H-optimus-0 is just the beginning. It marks the first in a long series of models we will create at Bioptimus, each more advanced and comprehensive than the last. Future models will not only be trained on an even larger number of pathology images from Europe, Asia and Africa but will also incorporate other modalities, such as genomics and proteomics. Our ultimate goal is to create the first multiscale foundation model of biology, capable of integrating diverse biological data and scales to enable scientific discoveries and accelerate biomedical innovations.”

You can access the model, detailed documentation, and research findings on our GitHub repository here.

About Bioptimus

Bioptimus is building the universal AI foundation model in biology to drive advancements in scientific research and biotechnological innovation. Leveraging a team of world-class experts, employing state-of-the-art AI technologies and accessing unique proprietary data at scale, we aim to fuel breakthrough discoveries and accelerate innovations in biomedicine and beyond. For more information, please visit

View source version on


About Business Wire

For more than 50 years, Business Wire has been the global leader in press release distribution and regulatory disclosure.

Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

Laserfiche Global Headquarters Achieves LEED Silver Certification23.7.2024 17:00:00 EEST | Press release

Laserfiche — the leading SaaS provider of intelligent content management and business process automation — announced today that its Long Beach-based global headquarters has been awarded LEED Silver certification. LEED (Leadership in Energy and Environmental Design), developed by the U.S. Green Building Council (USGBC), is the most widely used green building rating system in the world and an international symbol of excellence. Laserfiche achieved LEED Silver certification for implementing practical and measurable strategies and solutions in areas including sustainable site development, energy efficiency, materials selection, and indoor environmental quality. This press release features multimedia. View the full release here: Laserfiche's global headquarters in Long Beach, California. (Photo: Business Wire) The Laserfiche headquarters project integrated sustainability and environmental practices into the construction and overall d

Andersen Global Broadens Footprint in Czech Republic23.7.2024 16:30:00 EEST | Press release

Andersen Global advances its European valuation coverage through a Collaboration Agreement with Czech-based valuation firm Pražská Znalecká Kancelář (PZK). Led by managing partner Petr Smid and based in Prague, PZK provides services to domestic and international clients. The firm’s team specializes in valuation solutions for real estate, business advisory, securities, litigation, transfer pricing, mergers and acquisitions, and tax. “Collaborating with Andersen Global drives our firm’s development efforts forward as we continue to deliver integrated solutions and build long-lasting client relationships,” Petr said. “Together, with the member and collaborating firms, we will leverage our collective expertise to create unparalleled value for our clients.” “PZK’s commitment to excellence and extensive valuation expertise will bring immediate value to our clients,” said Global Chairman and CEO of Andersen Mark L. Vorsatz. “The Czech Republic is a critical market for our valuation platform i

DCO Calls for Urgent Discussions with Member States, Digital Experts to Address Recent Global IT Outage’s Implications23.7.2024 16:28:00 EEST | Press release

The Digital Cooperation Organization’s (DCO) General Secretariat said in a statement that it will hold urgent discussions with its Member States and digital economy experts to address the implications of the global IT outage that disrupted vital operations around the world, affecting critical business sectors like aviation, banking, broadcast media, software providers, and more. The DCO General Secretariat states that “the high level of impact the world witnessed as a result of the unfortunate outage is alarming and indicates the dire need for a more effective and agile international digital cooperation.” The incident raised questions on continuity and sustainability in a world rapidly moving towards being highly dependent on digital channels and platforms. It is very crucial that the international community develops proper policies and protocols to mitigate the risks of such incidents and ensure the continuity of essential operations. To this end, the DCO General Secretariat has calle

CSC and Palo Alto Networks Join Forces to Fortify Domain Security for Cortex XSOAR, XSIAM, and XPANSE Users and CSC Domain Registrar Clients23.7.2024 16:00:00 EEST | Press release

CSC, an enterprise-class domain registrar and world leader in mitigating domain security, domain name system (DNS), and digital brand threats, today announces a technical collaboration with Palo Alto Networks to boost domain security for users of Palo Alto Network’s Cortex XSOAR, XSIAM, and XPANSE solutions and for CSC's domain registrar clients. Under this collaboration, CSC will use domain name, DNS, and secure sockets layer (SSL) portfolio data—in conjunction with intelligence and capabilities within Cortex—to contextualize risks and facilitate the remediation of threats. This new integration pack for our CSCDomainManager℠ application programming interface (API) is now available for download via the Cortex marketplace. As part of the relationship, joint Cortex and CSC clients can also benefit from a complimentary, defined package of domain name and URL phishing takedowns that target corporate domain name portfolios. This will help secure clients against threat vectors targeting thei

SLB to Accelerate Co-Development of AI-Driven Digital Platform for Aker BP23.7.2024 16:00:00 EEST | Press release

Regulatory News: This press release features multimedia. View the full release here: (Photo: Business Wire) SLB and Aker BP today announced they have agreed a long-term partnership to co-develop an AI-driven digital platform for Aker BP to accelerate innovation and deliver substantial efficiency improvements across the company’s E&P operations. The new platform will leverage the Delfi™ digital platform to enable new digital solutions in the cloud for Aker BP. “By co-developing AI-powered digital technologies, we will transform Aker BP’s subsurface workflows, accelerating planning cycles, increasing production, and reducing costs across their entire E&P life cycle,” said Rakesh Jaggi, President, Digital & Integration, SLB. “We have made a long-term commitment with Aker BP to continuously improve the subsurface part of their platform, driving constant efficiency optimization and more sustainable energy production.” The partners wi

In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.

Visit our pressroom
HiddenA line styled icon from Orion Icon Library.Eye