Davos Alzheimer's Collaborative, World Economic Forum Announce Major Milestones in the Global Fight Against Alzheimer’s Disease
The Davos Alzheimer’s Collaborative (DAC) is a global multi-stakeholder partnership that is mobilizing the world against Alzheimer’s disease. DAC announced today it has nearly completed financing of its foundational phase and has launched several key initiatives to advance Alzheimer’s research, prevention and care to advance the fight against the disease.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20210921005348/en/
A recent WHO report shows that Alzheimer’s and dementia impacted more than 55 million families worldwide and cost the global economy approximately US$1.3 trillion in 2019. This annual cost is expected to rise to $2.8 trillion by 2030, based on predicted increases in cases and the cost of care. By averaging these numbers to assume an approximate annual cost of $2 trillion through 2030, we estimate the disease will cost the global economy a cumulative $20 trillion over the next decade.
Due to rapid gains in global life expectancy, more than 70% of Alzheimer’s cases will be in low- and middle-income countries (LMICs) by 2050, inhibiting their prospects for growth and exacerbating health and economic disparities between LMICs and higher-income countries. By contrast, nearly 80% of genomic analysis has come from people of European descent, even though more than 80% of the global population is not of European descent.
New advances in treatment have accelerated investment and innovation in the space, building momentum for change and increasing the urgency for healthcare systems to be prepared for major changes in how they care for patients with the disease in the coming years.
“Now is the time to act on Alzheimer’s. International bodies including the WHO, G7, and G20 have all made commitments in recent years that recognize the need to act together, act globally and act now to address this health crisis,” said George Vradenburg, Chair of DAC. “DAC is a response to these calls for action, bringing the speed and scale that has too often been lacking in previous efforts. The COVID-19 pandemic has shown us that a broad coalition of stakeholders working together can mobilize quickly to address a looming public health catastrophe. However, COVID-19 has also taught the world that we must have a robust preparedness plan – early and systematic testing and detection, timely access to real-world data, a standing, global, trial-ready system for developing and testing new therapies, and healthcare systems in high and low resource settings that are prepared to get the right intervention to the right patient at the right time. And, most importantly, we must include every nation and marshal every sector from the beginning to ensure a universal and equitable response.”
DAC is orchestrating an ambitious global effort to combat the Alzheimer’s crisis by linking, scaling and building on existing efforts across every sector. DAC is advancing this mission through several key initiatives, built on the scientific and business input of hundreds of experts in the space:
- Global Cohorts: Working with the International One Hundred K+ Cohorts Consortium (IHCC) and other partners, DAC is building a cohort of one million people who reflect the disease in all its global diversity, with data available to researchers everywhere in order to marshal the world’s scientific and industrial talent to find new clues to stopping Alzheimer’s. In our first six months of operations, we have linked 12 cohorts spanning Africa, Asia and South America, with more than 20 additional cohorts under consideration. We have stress-tested this diverse combined cohort using our Polygenic Risk Score (PRS) Feasibility Pilot, a first-of-its-kind, transethnic and transracial analysis of genetic data from approximately 100,000 people with Alzheimer’s.
- Clinical Trials: DAC is helping reduce the time and cost of clinical trials while improving their quality to accelerate the innovations that families and countries so desperately need. Working with the Global Alzheimer’s Platform, we are linking a network of 90 trial sites in North America with over a dozen European trial sites to accelerate key studies and implement novel trial designs, and we also are surveying site capacity across the rest of the world to extend future trials to other continents. We’re also designing a novel African clinical trial in Alzheimer’s disease and have secured a commitment from Roivant Social Ventures to make available an investigational new drug for use in this trial.
- Healthcare System Preparedness: DAC is investing in healthcare systems to produce new learnings using new technologies and protocols to improve the clinical care of people with, or at risk of, Alzheimer’s. To date, we have secured healthcare system partners in the U.S., Brazil, Mexico, Scotland, Japan and Jamaica to pilot the use of blood biomarkers and technology-enabled methods in clinical practice, including earlier detection of Alzheimer’s disease. We also held our first “Learning Laboratory” of these flagship health systems to share their innovative practices with approximately 200 attendees from health systems and national health ministries, including representatives of seven governments from around the world. The World Health Organization has agreed to serve as a technical advisor on these efforts.
“Alzheimer’s disease recognizes no boundaries. Yet too often our response is fragmented — leaving patients, families and researchers to face this burden alone, especially in low- and middle-income countries,” said Dr. Margaret Chan, Emeritus WHO Director General and Founding Dean of the Tsinghua Vanke School of Public Health. “The work of the Davos Alzheimer’s Collaborative, and its commitment to lead a new fight through new public-private partnerships, will help save countless lives and trillions of dollars lost to Alzheimer’s each year.”
In addition to these initiatives, DAC has achieved several business milestones that will lay the foundation for our continued work to eliminate the burden of Alzheimer’s.
DAC is now headquartered in Switzerland, with IRS 501c3 affiliate status in the U.S. We are also completing our foundational phase fund-raise with $25 million in commitments to advance our projects, in addition to invaluable contributions of time and talent, from supporters including Eli Lilly & Company, Roche, Biogen, Eisai, Otsuka, C2N, Cognivue, Linus Health and Cogstate.
“The progress made by the Davos Alzheimer’s Collaborative since its launch in January signals the urgent need for a collective global response to the growing public health crises of Alzheimer’s disease,” said Klaus Schwab, Founder and Executive Chairman of the World Economic Forum. “Following in the footsteps of initiatives incubated at the World Economic Forum, such as the Global Alliance for Vaccines and Immunization (GAVI) and the Coalition for Epidemic Preparedness Innovations (CEPI), the Davos Alzheimer’s Collaborative is bringing new cooperative energy and global vision to the fight against this disease that brings suffering to hundreds of millions of people, families and caregivers around the world.”
DAC’s founding Board members will guide the collaborative toward its 2022 priorities and beyond. A full list of DAC leadership group members is available here.
“DAC is bringing together the best minds to improve the speed and scale of the scientific fight against Alzheimer’s,” said Elias Zerhouni, Professor Emeritus, Johns Hopkins University; Former Director, National Institutes of Health and Former President of R&D, Sanofi. “We’ve built a plan of action informed by experts in Alzheimer’s disease, data science and digital technologies, and we are pleased to start executing it through these initiatives.”
DAC intends to announce further progress toward these goals during the Lausanne VIII Workshop in November 2021 and the World Economic Forum annual meeting in January 2022.
About the Davos Alzheimer’s Collaborative
Launched at the World Economic Forum’s 2021 meeting on The Davos Agenda, The Davos Alzheimer’s Collaborative is a multi-stakeholder partnership committed to aligning stakeholders with a new vision for our collective global response against the challenges Alzheimer’s presents to patients, caregivers and healthcare infrastructures. Convened by The World Economic Forum and The Global CEO Initiative on Alzheimer’s Disease (CEOi) and fueled by a mission of service to the estimated 150 million families and half a billion people inevitably impacted by this disease by 2050, DAC is a collaborative for the benefit of all people, in all places.
Note to Editors
Additional quotes from DAC’s leadership and partners are attached.
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
Media Contact: Katie Hatcher, KHatcher@webershandwick.com
About Business Wire
For more than 50 years, Business Wire has been the global leader in press release distribution and regulatory disclosure.
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
SES-17 Successfully Launched on Ariane 524.10.2021 07:08:00 EEST | Press release
SES announced today that the SES-17 satellite was successfully launched into space onboard an Ariane 5 launcher operated by Arianespace from the Europe’s Spaceport in Kourou, French Guiana at 11:10 pm local time (02:10 am UTC). This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20211023005019/en/ SES-17 Successfully Launched on Ariane 5 (Photo: Business Wire) The multi-mission Ka-band satellite will provide comprehensive coverage across the Americas, the Caribbean and the Atlantic Ocean. From its orbital slot of 67.1 degrees West orbital slot, the very high throughput geostationary (GEO) satellite incorporating cutting-edge technologies is set to deliver the best connectivity experience for SES customers operating in the aeronautical, maritime, enterprise, and government markets. Built by Thales Alenia Space, SES-17 marks an important milestone in satellite technology as the first Ka-band geostationary satellite to embark a fully
Peru Holds a Ribbon Cutting Ceremony at Its Pavilion at Dubai Expo and Wins 4 World Travel Awards22.10.2021 20:15:00 EEST | Press release
The Dubai World Expo took place in an electrifying musical atmosphere where thousands of attendees were captivated by the variety of artistic, musical and cultural expressions that characterize the different regions of Peru. All this was part of the inauguration of the Peru Pavilion at the most important cultural event in the world. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20211022005454/en/ Peru inaugurated its Pavilion at Expo 2020 Dubai and received four awards from the “Tourism Oscars.” (Photo: Business Wire) The Peru Pavilion was inaugurated by the Commissioner General for Peru at the Expo, Amora Carbajal, and Najeeb Mohammed Al-Ali, Executive Director of Expo 2020 Dubai, in front of official representatives from different country pavilions. “The purpose of the pavilion is to offer a complete learning experience about ancient Peruvian wisdom throughout the visit, communicating the importance of the heritage, biodive
Schlumberger Announces Third-Quarter 2021 Results22.10.2021 13:50:00 EEST | Press release
Schlumberger Limited (NYSE: SLB) today reported results for the third-quarter 2021. Third-Quarter Results (Stated in millions, except per share amounts) Three Months Ended Change Sept. 30, 2021 Jun. 30, 2021 Sept. 30, 2020 Sequential Year-on-year Revenue* $5,847 $5,634 $5,258 4% 11% Income (loss) before taxes - GAAP basis $691 $542 $(54) 28% n/m Net income (loss) - GAAP basis $550 $431 $(82) 28% n/m Diluted EPS (loss per share) - GAAP basis $0.39 $0.30 $(0.06) 30% n/m Adjusted EBITDA** $1,296 $1,198 $1,018 8% 27% Adjusted EBITDA margin** 22.2% 21.3% 19.4% 90 bps 280 bps Pretax segment operating income** $908 $807 $575 12% 58% Pretax segment operating margin** 15.5% 14.3% 10.9% 120 bps 460 bps Net income, excluding charges & credits** $514 $431 $228 19% 126% Diluted EPS, excluding charges & credits** $0.36 $0.30 $0.16 20% 125% Revenue by Geography International $4,675 $4,511 $4,210 4% 11% North America* 1,129 1,083 1,034 4% 9% Other 43 40 14 n/m n/m $5,847 $5,634 $5,258 4% 11% *Schlumbe
Disruptive.Asia: Huawei's Ryan Ding and Peng Song Discuss How Operators Can Leverage Connectivity to Unlock New Growth22.10.2021 13:30:00 EEST | Press release
Disruptive.Asia reported that Ryan Ding and Peng Song stressed the growing importance of connectivity in driving industry growth and generating value amid a rapidly evolving landscape at the 7th Ultra-Broadband Forum (UBBF 2021) in Dubai, which is jointly hosted by the UN Broadband Commission and Huawei. Ding, Executive Director of the Board and President of the Carrier Business Group, Huawei, said that connectivity has made it possible to innovate, especially in a digital age where increasing efficiency has become paramount. The pandemic has also ushered a paradigm shift in connectivity, as homes turned into multi-functional centers for education, work, and business. It became increasingly clear that connectivity not only drives digital economies forward but also maintains the functioning of society. Peng, President of the Global Carrier Marketing & Solution Sales Department, Huawei, said that looking at connectivity through Huawei's C.A.F (Coverage, Architecture and Fusion) model can
Suzano Brings Its Target for Capturing 40 Million Tons of Carbon From the Atmosphere Forward To 202522.10.2021 13:19:00 EEST | Press release
Suzano, the world's leading eucalyptus pulp producer and a global benchmark in the manufacture of bioproducts developed from eucalyptus, announces today that it has revised one of its 14 long-term goals – collectively known as Suzano’s “Commitments to Renewing Life”*. Suzano’s goal to remove 40 million tons of carbon from the air by 2030 has been brought forward by five years to 2025. With this revision, Suzano reinforces its capacity to make an even more positive contribution to the planet's climate by achieving net carbon removals from the atmosphere at a faster pace than previously expected. The new five-year target will be supported by the expansion of Suzano’s forest covering which will involve both an uplift in commercial planting operations and setting aside new designated conservation areas that were previously anthropized. Alongside these improvements, Suzano will maintain its focus on reducing carbon emissions across its own operations and supply chain and will continue to im
AntChain Launches Its First Security Chip and New Blockchain Platform Powered by Privacy Computing Technology22.10.2021 13:01:00 EEST | Press release
AntChain, the flagship technology brand of Ant Group, today unveiled two new products at the Apsara Conference 2021 in Hangzhou – the FAIR platform and the T1 security chip – to ensure the security and trustworthiness of data flows within blockchain networks. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20211022005166/en/ Yan Ying, technical director of AntChain, unveiled the FAIR platform at the Apsara Conference on October 22, 2021. (Photo: Business Wire) Based on AntChain’s upgraded technical architecture, the FAIR platform natively integrates privacy-preserving computation (PPC) and blockchain technologies in a unified platform, unleashing the value of data flows over their entire lifecycle. FAIR is designed to address pain points in multi-party collaboration on data flows, which is increasingly common on the industrial internet. It replaces traditional “PPC plus blockchain” dual-system architecture, integrating the two
Total Telecom: Maximizing the Value of Connectivity22.10.2021 13:00:00 EEST | Press release
Total Telecom reported that i ndustry leaders gathered recently at Ultra-Broadband Forum 2021, organized by UN Broadband Commission and Huawei, held in Dubai to discuss building future-proof networks sustainably. Total Telecom thinks that the expectations from digital connectivity have been redefined in the last one year. From conducting financial transactions online to remote factory management, the digital way of life is becoming pervasive. "Connectivity reshaped how we live and work when the pandemic hit in 2020. Connectivity is more than an expansion of functions, it is an emotional bond. As long as there is connectivity, there is a bond. Where there is connectivity, there is innovation. It presents us with unlimited possibilities. I believe in our shared mission to create a connected world," says Ryan Ding, Executive Director of the Board, President of the Carrier BG, Huawei, in his inaugural address. The C.A.F (Coverage, Architecture and Fusion) model is emerging as a way for the
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.Visit our pressroom